HLA-B*44 is associated with a more than twentyfold increase in cyclic citrullinated peptide antibody serum level in Croatian patients with seropositive rheumatoid arthritis
HLA-B*44 is associated with a twenty-fold increase in anti-CCP serum levels. HLA-A*03 and HLA-DRB1*04 have a positive trend towards a twenty-fold increase in anti-CCP levels. Earlier aggressive therapy in these patients can prevent such an extreme increase in antibody levels.
Authors
- Daniela Šošo (ORCID: https://orcid.org/0000-0001-6890-4768)
- Esma Čečuk-Jeličić (ORCID: https://orcid.org/0000-0002-2744-2963)
- Darko Kero (ORCID: https://orcid.org/0000-0002-8091-6347)
- Daniela Marasović Krstulović (ORCID: https://orcid.org/0000-0002-7026-8825)
- Jure Aljinović (ORCID: https://orcid.org/0000-0001-9546-3777)
- Dijana Perković (ORCID: https://orcid.org/0000-0002-6188-0502)
- Ivanka Marinović (ORCID: https://orcid.org/0000-0002-0960-157X)
- Marin Petrić (ORCID: https://orcid.org/0000-0002-5282-9633)
- Sonja Jaman
- Dora Dujmović
Institutions
- Croatian Institute of Transfusion Medicine (HR)
- University of Split (HR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1371/journal.pone.0334551
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 0.00