Exploring the Shared Genetic Architectures Between Primary Open-Angle Glaucoma and Visual Pathway Regions in the Brain
Our findings suggest a genetic overlap between POAG and the volumes of visual pathway regions, including shared candidate causal genes. Further investigations are required to elucidate the specific role of the shared genes in the etiology of POAG and to assess their potential as neuroprotective drug targets.
Authors
- Puya Gharahkhani (ORCID: https://orcid.org/0000-0002-4203-5952)
- Asma M. Aman
- Stuart MacGregor (ORCID: https://orcid.org/0000-0001-6731-8142)
- Santiago Díaz‐Torres (ORCID: https://orcid.org/0000-0002-5442-9211)
Institutions
- Queensland University of Technology (AU)
- The University of Queensland (AU)
- QIMR Berghofer Medical Research Institute (AU)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1167/iovs.66.15.11
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Medical Research Council
- National Health and Medical Research Council