Canady Helios Cold Plasma Induces Non-Thermal (24 °C), Non-Contact Irreversible Electroporation and Selective Tumor Cell Death at Surgical Margins
This study demonstrates CHCP as a non-thermal (24 °C), non-contact plasma-based IRE platform which induces controlled membrane permeabilization and selective cancer cell death. CHCP offers a translational strategy to eradicate residual tumor cells at the surgical margins, and prevent local recurrence, positioning it as a versatile adjunct in precision surgical oncology.
Authors
- Olivia Jones (ORCID: https://orcid.org/0000-0001-5497-6381)
- Michael Keidar (ORCID: https://orcid.org/0000-0003-0869-4310)
- Saravana R. K. Murthy
- Jerome Canady (ORCID: https://orcid.org/0009-0000-9409-5431)
- Aviram Nissan (ORCID: https://orcid.org/0000-0003-0701-2293)
- Taisen Zhuang
- Yasmine Dakak
Institutions
- University of Maryland, Baltimore (US)
- University of Maryland Medical Center (US)
- George Washington University (US)
- Rebecca Sieff Hospital (IL)
Publication Details
- Journal
- Cancers
- Published
- 2025-12-02
- DOI
- https://doi.org/10.3390/cancers17233869
- Citations
- 1
- Primary Topic
- Plasma Applications and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 1.36