Investigation for atherosclerotic plaque rupture with thrombosis in mice based on single-cell sequencing and bioinformatics analysis
<i>COL5A1</i>, <i>VCAN</i>, <i>PTGS2</i>, <i>ITGAV</i> and <i>ITGA8</i> might be novel biomarkers for atherosclerotic plaque rupture with thrombosis. <i>ITGAV</i> and <i>VCAN</i> might take part in the process atherosclerotic plaque rupture with thrombosis via cell adhesion function.
Authors
- Guofeng Yan (ORCID: https://orcid.org/0000-0003-2328-7916)
- Takashi Yao (ORCID: https://orcid.org/0000-0003-2287-7658)
- Shuxuan Jin
- Peng Nie (ORCID: https://orcid.org/0000-0001-8359-9319)
- Yao Li (ORCID: https://orcid.org/0000-0003-4330-6440)
- Jun Pu (ORCID: https://orcid.org/0000-0003-2240-5108)
- Fang Wan (ORCID: https://orcid.org/0000-0001-5107-9757)
Institutions
- Shanghai Jiao Tong University (CN)
- Renji Hospital (CN)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-12-03
- DOI
- https://doi.org/10.3389/fcvm.2025.1658170
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Shanghai
- National Natural Science Foundation of China
- Natural Science Foundation for Young Scientists of Shanxi Province
- Young Scientists Fund