Gender Minority Stress and Resilience, Mental Health and Wellbeing in Transgender and Gender-Diverse Individuals: A Narrative Review

Abstract Purpose of Review Transgender and gender diverse (TGD) individuals experience disproportionate mental health burdens compared to cisgender heterosexual, lesbian, gay and bisexual populations. The Gender Minority Stress and Resilience (GMSR) framework explains how systemic prejudice drives these disparities. Our narrative review synthetizes recent expansions of the model, including novel psychological mediators, integrative frameworks and criticisms. Recent Findings The literature underscores the complex, socially embedded relationships between GMSR factors and mental health. Moreover, the distress related to gender incongruence may be reconceptualized as emerging from dynamic transactions between the social settings and the individual. Social invalidation, rejection and non-affirmation of gender identity in the developmental age can also impact wellbeing as forms of Gender Minority Stress. Summary Attributing mental health challenges to internal identity processes needs to shift toward systemic invalidation as a key driver, centering the diversity of TGD experiences, beyond narratives of suffering, as positive journeys of gender affirmation.

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Publication Details

Journal
Current Sexual Health Reports
Published
2025-12-03
DOI
https://doi.org/10.1007/s11930-025-00414-8
Primary Topic
LGBTQ Health, Identity, and Policy
Type
article
Field-Weighted Citation Impact
0.00

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article

Gender Minority Stress and Resilience, Mental Health and Wellbeing in Transgender and Gender-Diverse Individuals: A Narrative Review

Ilaria Turone, Maria Lucia Pop, Gianluca Serafini, Michael Winterdahl et al.
Current Sexual Health Reports
LGBTQ Health, Identity, and Policy
article

Gender Minority Stress and Resilience, Mental Health and Wellbeing in Transgender and Gender-Diverse Individuals: A Narrative Review

Ilaria Turone, Maria Lucia Pop, Gianluca Serafini, Michael Winterdahl, Erin Petersen
article en

Abstract

Abstract Purpose of Review Transgender and gender diverse (TGD) individuals experience disproportionate mental health burdens compared to cisgender heterosexual, lesbian, gay and bisexual populations. The Gender Minority Stress and Resilience (GMSR) framework explains how systemic prejudice drives these disparities. Our narrative review synthetizes recent expansions of the model, including novel psychological mediators, integrative frameworks and criticisms. Recent Findings The literature underscores the complex, socially embedded relationships between GMSR factors and mental health. Moreover, the distress related to gender incongruence may be reconceptualized as emerging from dynamic transactions between the social settings and the individual. Social invalidation, rejection and non-affirmation of gender identity in the developmental age can also impact wellbeing as forms of Gender Minority Stress. Summary Attributing mental health challenges to internal identity processes needs to shift toward systemic invalidation as a key driver, centering the diversity of TGD experiences, beyond narratives of suffering, as positive journeys of gender affirmation.

Current Sexual Health ReportsVol. 17(1)
Aarhus University (DK), Aalborg University Hospital (DK), Ospedale Policlinico San Martino (IT), University of Genoa (IT)
Aalborg Universitet, Università degli Studi di Genova, Aalborg Universitetshospital
Openalex Percentile: Top 57%
LGBTQ Health, Identity, and Policy
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Gender Minority Stress and Resilience, Mental Health and Wellbeing in Transgender and Gender-Diverse Individuals: A Narrative Review — Ilaria Turone, Maria Lucia Pop, et al. · Current Sexual Health Reports (2025) | TGRS Research Map | TGRS