Preconception health as a target for improved pregnancy outcomes: Where do we go from here?

Preconception health status, especially of women, but also of men, is known to influence pregnancy outcomes. Despite knowledge of the growing importance of preconception health, numerous challenges remain for conducting research in this population and delivering appropriate clinical care. The 2023 Global Pregnancy Collaboration annual workshop focused on exploring preconception health as it relates to adverse pregnancy outcomes. Here we summarize the proceedings and the current state of the science. We particularly focus on quantifying the exposome as a rich target for investigation of factors that increase the risk for and/ or contribute to preeclampsia and other adverse pregnancy outcomes. We conclude with recommendations for the scientific and clinical community to address knowledge gaps regarding the links between preconception health and adverse pregnancy outcomes.

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Publication Details

Journal
Pregnancy Hypertension
Published
2025-12-03
DOI
https://doi.org/10.1016/j.preghy.2025.101395
Primary Topic
Pregnancy and preeclampsia studies
Type
article
Field-Weighted Citation Impact
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article

Preconception health as a target for improved pregnancy outcomes: Where do we go from here?

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Preconception health as a target for improved pregnancy outcomes: Where do we go from here?

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article en

Abstract

Preconception health status, especially of women, but also of men, is known to influence pregnancy outcomes. Despite knowledge of the growing importance of preconception health, numerous challenges remain for conducting research in this population and delivering appropriate clinical care. The 2023 Global Pregnancy Collaboration annual workshop focused on exploring preconception health as it relates to adverse pregnancy outcomes. Here we summarize the proceedings and the current state of the science. We particularly focus on quantifying the exposome as a rich target for investigation of factors that increase the risk for and/ or contribute to preeclampsia and other adverse pregnancy outcomes. We conclude with recommendations for the scientific and clinical community to address knowledge gaps regarding the links between preconception health and adverse pregnancy outcomes.

Pregnancy HypertensionVol. 43
University of Vermont (US), Brigham and Women's Hospital (US), University College Hospital (GB), Lund University (SE), University of Münster (DE), Erasmus MC (NL), Magee-Womens Research Institute (US), NIHR Southampton Biomedical Research Centre (GB), University of Southampton (GB), University College London (GB), The Ohio State University (US)
Openalex Percentile: Top 52%
Pregnancy and preeclampsia studies
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