Efficacy of Intraoperative Widening of Surgical Resection Margins for Non-Palpable Breast Cancer: An Analysis of 771 Breast-Conserving Surgeries

IWSM can help increase the efficacy of tumorectomies for non-palpable breast cancer lesions. However, in the majority of cases, healthy breast tissue is removed as well. Tumor and patient characteristics may help in the selection of cases for which IWSM reduces the positive margin rate and the number of unnecessary procedures.

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Publication Details

Journal
Cancers
Published
2025-11-28
DOI
https://doi.org/10.3390/cancers17233827
Primary Topic
Breast Cancer Treatment Studies
Type
article
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article

Efficacy of Intraoperative Widening of Surgical Resection Margins for Non-Palpable Breast Cancer: An Analysis of 771 Breast-Conserving Surgeries

Mustafa Yenigün, Marcel Kapahnke, Roberta Decio, Angela L. Scarano et al.
Cancers
Breast Cancer Treatment Studies
article

Efficacy of Intraoperative Widening of Surgical Resection Margins for Non-Palpable Breast Cancer: An Analysis of 771 Breast-Conserving Surgeries

Mustafa Yenigün, Marcel Kapahnke, Roberta Decio, Angela L. Scarano, Ulrike Perriard, Simone Schiaffino, Claudia Canonica, Maria Luisa Gasparri, Carola Catanese, Camilla Favero, Nickolas Peradze, Eric Ramazzotti, D. Spinelli, Virginia Casati, Clémence Aellen
article en

Abstract

IWSM can help increase the efficacy of tumorectomies for non-palpable breast cancer lesions. However, in the majority of cases, healthy breast tissue is removed as well. Tumor and patient characteristics may help in the selection of cases for which IWSM reduces the positive margin rate and the number of unnecessary procedures.

CancersVol. 17(23)
Ospedale regionale di Lugano (CH), Ospedale San Giovanni Bellinzona (CH), Ospedale Regionale di Bellinzona e Valli (CH), Istituto Cantonale di Patologia (CH), Clinica Luganese Moncucco (CH), Università della Svizzera italiana (CH)
Openalex Percentile: Top 53%
Breast Cancer Treatment Studies
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Efficacy of Intraoperative Widening of Surgical Resection Margins for Non-Palpable Breast Cancer: An Analysis of 771 Breast-Conserving Surgeries — Mustafa Yenigün, Marcel Kapahnke, et al. · Cancers (2025) | TGRS Research Map | TGRS