QbD-driven solid dispersion development for enhanced solubility and dissolution of the BCS Class II drug voriconazole as a model drug

Voriconazole (VC), a second-generation triazole antifungal, suffers from low aqueous solubility (∼0.5 mg mL −1 ), which restricts its oral bioavailability.

Authors

Bhaskar Daravath (ORCID: https://orcid.org/0000-0001-8181-4134)
UDAY KIRAN KUMMARI
C RAVITEJA

Institutions

GITAM University (IN)

Publication Details

Journal: RSC Pharmaceutics
Published: 2025-12-03
DOI: https://doi.org/10.1039/d5pm00241a
Primary Topic: Antifungal resistance and susceptibility
Type: article
Field-Weighted Citation Impact: 0.00

Funders

Gandhi Institute of Technology and Management

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article

QbD-driven solid dispersion development for enhanced solubility and dissolution of the BCS Class II drug voriconazole as a model drug

Bhaskar Daravath, UDAY KIRAN KUMMARI, C RAVITEJA

Dec 3, 2025

RSC Pharmaceutics

Antifungal resistance and susceptibility

article

QbD-driven solid dispersion development for enhanced solubility and dissolution of the BCS Class II drug voriconazole as a model drug

Bhaskar Daravath, UDAY KIRAN KUMMARI, C RAVITEJA

December 3, 2025article en

Abstract

Voriconazole (VC), a second-generation triazole antifungal, suffers from low aqueous solubility (∼0.5 mg mL −1 ), which restricts its oral bioavailability.

RSC PharmaceuticsVol. 3(2)

GITAM University (IN)

Gandhi Institute of Technology and Management

Openalex Percentile: Top 56%

Antifungal resistance and susceptibility

DOI Open Access PDF OpenAlex

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QbD-driven solid dispersion development for enhanced solubility and dissolution of the BCS Class II drug voriconazole as a model drug — Bhaskar Daravath, UDAY KIRAN KUMMARI, et al. · RSC Pharmaceutics (2025) | TGRS Research Map | TGRS