Thyrotropin Directly Affects Cardiac Electrophysiology and Is Associated With AF Prevalence
Individuals with SH exhibit an increased prevalence of AF, which is likely in part due to a direct effect of TSH on ion channel expression in cardiomyocytes via the TSHR/cAMP/PKA pathway.
Authors
- Ζoltan Κender (ORCID: https://orcid.org/0000-0003-0745-1587)
- Norbert Frey (ORCID: https://orcid.org/0000-0001-7611-378X)
- Ann‐Kathrin Rahm (ORCID: https://orcid.org/0000-0002-7509-887X)
- Heike Gampp
- Xuehui Fan (ORCID: https://orcid.org/0000-0001-9040-1155)
- Rasmus Rivinius (ORCID: https://orcid.org/0000-0003-1146-6319)
- Zenghui Meng
- Dominik Seibold
- Christine Mages (ORCID: https://orcid.org/0000-0002-7617-1418)
- Dierk Thomas (ORCID: https://orcid.org/0000-0002-5687-7843)
- Jordi Heijman (ORCID: https://orcid.org/0000-0002-1418-108X)
- Pascal Syren (ORCID: https://orcid.org/0000-0003-0732-8810)
- Maximilian N. Wunsch (ORCID: https://orcid.org/0000-0002-9735-8097)
- Axel Schöffel
- Nina D. Ullrich (ORCID: https://orcid.org/0000-0002-1077-3125)
- Patrick Lugenbiel (ORCID: https://orcid.org/0000-0003-3886-0930)
- Yingrui Li (ORCID: https://orcid.org/0000-0001-6630-1277)
- Carsten Sticht (ORCID: https://orcid.org/0000-0003-3596-6094)
- Xiaobo Zhou (ORCID: https://orcid.org/0000-0002-5895-0127)
- Hauke Hund
- Wen Xin (ORCID: https://orcid.org/0009-0003-1239-7850)
- Chen Yan (ORCID: https://orcid.org/0000-0001-5803-3102)
- Xenia C. Kramp
- Ibrahim Akin
- j. william pfeiffer
- Teresa Caspari
Institutions
- University of Bern (CH)
- Medical University of Graz (AT)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Maastricht University (NL)
- German Centre for Cardiovascular Research (DE)
- Norwegian Womens Public Health Association (NO)
- University Medical Centre Mannheim (DE)
Publication Details
- Journal
- Circulation Arrhythmia and Electrophysiology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1161/circep.125.013775
- Citations
- 1
- Primary Topic
- Thyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.29