The Kv10.1 potassium channel, driver of hypoxia-induced EMT and breast cancer cell aggressiveness
We demonstrated, for the first time, the impact of Kv10.1 channel in hypoxia-induced aggressivity of breast cancer cells demonstrating its potential use as a complementary target to fight against metastasis development.
Authors
- Stéphanie Guénin (ORCID: https://orcid.org/0000-0002-0514-982X)
- Alban Girault (ORCID: https://orcid.org/0000-0001-5478-9340)
- Halima Ouadid‐Ahidouch (ORCID: https://orcid.org/0009-0009-8266-5631)
- Robert‐Alain Toillon (ORCID: https://orcid.org/0000-0001-5483-2118)
- Nicolas Jonckheere (ORCID: https://orcid.org/0000-0002-0496-0661)
- Fabien Gosselet (ORCID: https://orcid.org/0000-0002-0481-5026)
- Minna Laine (ORCID: https://orcid.org/0000-0003-3337-3500)
- Caroline Mysiorek (ORCID: https://orcid.org/0000-0003-2338-8821)
- Laurent Gutierrez (ORCID: https://orcid.org/0000-0003-4829-8531)
- Marie‐Pierre Dehouck (ORCID: https://orcid.org/0000-0002-9217-3202)
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université de Lille (FR)
- Centre Hospitalier Universitaire de Lille (FR)
- CANTHER - Hétérogénéité, Plasticité et Résistance aux Thérapies des Cancers (FR)
- Université d'Artois (FR)
- Université de Picardie Jules Verne (FR)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-10-24
- DOI
- https://doi.org/10.1186/s12935-025-04020-5
- Primary Topic
- Ion channel regulation and function
- Type
- article
- Field-Weighted Citation Impact
- 0.00