Mechanical Aspiration Thrombectomy Versus Conventional Treatment in Patients With Lower Extremity Acute Limb Ischemia

Compared with CT, MAT resulted in significantly improved final TIMI flow grades and fewer minor complications in patients with LE-ALI.Clinical ImpactThe present study establishes mechanical aspiration thrombectomy (MAT) using the Indigo System as a safe and efficacious alternative to conventional treatment for lower extremity acute limb ischemia. MAT resulted in superior final TIMI flow grades and a significantly reduced incidence of minor complications, with comparable rates of limb salvage and overall survival. These findings underscore MAT's potential to achieve more effective thrombus removal while minimizing procedural morbidity. For clinical practice, MAT may represent an advancement in endovascular management, offering enhanced technical performance and improved safety profiles in the treatment of this critical vascular emergency.