Artificial intelligence diagnostics for bladder tumor identification and grade prediction depend on narrow band imaging cystoscopy

The effective treatment of bladder cancer depends on early evaluation through cystoscopy. Given the clinical importance of distinguishing the tumor grade, we report the application of the AI-assisted NBI Cystoscopy Diagnostic System (AINCDS). The AINCDS consists of (1) dual-channel feature extraction module, (2) lesion segmentation module based on feature pyramids, and (3) a multi-task classification module. AINCDS achieved an accuracy for identifying bladder cancer of 0.919 (95% CI = 0.896 to 0.938). For the prediction of tumor grade, the accuracy was 0.764 (95% CI = 0.714 to 0.810). The AINCDS demonstrates similar ability comparable to urologists with over 10 years' experience. With the assistance of AINCDS, the tumor grade prediction accuracy of urologists with 1-3 years' experience improved from 0.667 to 0.793. AINCDS can assist in the diagnosis of bladder cancer and prediction of tumor grade, offering the potential to improve the accuracy of lesion assessment and reduce the workload of urologists.

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Publication Details

Journal
iScience
Published
2025-12-03
DOI
https://doi.org/10.1016/j.isci.2025.114309
Primary Topic
Bladder and Urothelial Cancer Treatments
Type
article
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article

Artificial intelligence diagnostics for bladder tumor identification and grade prediction depend on narrow band imaging cystoscopy

Guangping Wu, Yinchao Wang, Chuanpeng Li, Yao-Zhong Zhang et al.
iScience
Bladder and Urothelial Cancer Treatments
article

Artificial intelligence diagnostics for bladder tumor identification and grade prediction depend on narrow band imaging cystoscopy

Guangping Wu, Yinchao Wang, Chuanpeng Li, Yao-Zhong Zhang, Wenqiang Qi, Xiaoyi Zhang, Jun Chen, Benkang Shi, H. Liang
article en

Abstract

The effective treatment of bladder cancer depends on early evaluation through cystoscopy. Given the clinical importance of distinguishing the tumor grade, we report the application of the AI-assisted NBI Cystoscopy Diagnostic System (AINCDS). The AINCDS consists of (1) dual-channel feature extraction module, (2) lesion segmentation module based on feature pyramids, and (3) a multi-task classification module. AINCDS achieved an accuracy for identifying bladder cancer of 0.919 (95% CI = 0.896 to 0.938). For the prediction of tumor grade, the accuracy was 0.764 (95% CI = 0.714 to 0.810). The AINCDS demonstrates similar ability comparable to urologists with over 10 years' experience. With the assistance of AINCDS, the tumor grade prediction accuracy of urologists with 1-3 years' experience improved from 0.667 to 0.793. AINCDS can assist in the diagnosis of bladder cancer and prediction of tumor grade, offering the potential to improve the accuracy of lesion assessment and reduce the workload of urologists.

iScienceVol. 29(2)
Albert Einstein College of Medicine (US), Jacobi Medical Center (US), People’s Hospital of Rizhao (CN), Shandong Iron and Steel Group (China) (CN), Qilu Hospital of Shandong University (CN)
Openalex Percentile: Top 43%
Bladder and Urothelial Cancer Treatments
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