Psychological distress predicts disease activity in inflammatory bowel disease: Results from the mind-body IBD longitudinal study
Psychological distress exacerbates symptoms and economic cost. Poor sleep partially mediates the relationship between distress and SRDA, but not inflammation. Psychological interventions that focus on improving sleep could be cost-effective ways to improve mental health and symptom burden, with downstream impact on healthcare utilisation and productivity losses.
Authors
- Rona Moss‐Morris (ORCID: https://orcid.org/0000-0002-2927-3446)
- Ailsa L Hart (ORCID: https://orcid.org/0000-0002-7141-6076)
- Natasha Seaton (ORCID: https://orcid.org/0000-0002-1088-1396)
- Joanna L. Hudson (ORCID: https://orcid.org/0000-0003-0672-2621)
- Valeria Mondelli (ORCID: https://orcid.org/0000-0001-8690-6839)
- L.R. Raymond
- Pooja Schmill (ORCID: https://orcid.org/0009-0003-2146-6731)
Institutions
- King's College London (GB)
- St Mark's Hospital (GB)
- Imperial College London (GB)
Publication Details
- Journal
- Brain Behavior & Immunity - Health
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1016/j.bbih.2025.101147
- Citations
- 1
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- National Institute for Health and Care Research
- Department of Health and Social Care
- King's College London
- NIHR Maudsley Biomedical Research Centre
- Medical Research Council