Topical Omidenepag Isopropyl Lowers Intraocular Pressure in Normal and Glaucomatous Cats: A Pilot Study
A single topical drop of 0.002% OMDI significantly lowers IOP in normal and FCG cats without inducing miosis. Our findings support that topical selective EP2 agonists may be a promising therapeutic option for feline glaucoma and provide information relevant to dosing intervals for future studies.
Authors
- Virginia Mathu
- Julie A. Kiland (ORCID: https://orcid.org/0000-0002-9019-2346)
- Kazuya Oikawa (ORCID: https://orcid.org/0000-0003-2202-4786)
- Gillian J. McLellan (ORCID: https://orcid.org/0000-0002-6505-7476)
- Amit Rai (ORCID: https://orcid.org/0009-0009-9037-325X)
- Hayden G. Zaluckyj
Institutions
- McPherson College (US)
- University of Wisconsin–Madison (US)
Publication Details
- Journal
- Veterinary Ophthalmology
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1111/vop.70125
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Research to Prevent Blindness
- University of Wisconsin-Madison
- National Institutes of Health