Ruthenium Complexes in Protein Science: Heading a New Generation of Therapeutic and Analytical Tools
Abstract Ruthenium complexes are distinguished by their versatile coordination chemistry, redox behaviors and photochemical properties. In recent years, this tunability has enabled precise control over their interactions with peptides and proteins, opening new avenues in therapeutic and analytical applications. This minireview provides a concise overview of the growing role of ruthenium complexes in protein science, with a focus on latest advances in protein targeting, inhibition, labelling, and sensing.
Authors
- Sylvestre Bonnet (ORCID: https://orcid.org/0000-0002-5810-3657)
- Liyan Zhang (ORCID: https://orcid.org/0009-0000-4824-3931)
- Yun Chen (ORCID: https://orcid.org/0000-0003-3948-5626)
Institutions
- Leiden University (NL)
- Nanyang Technological University (SG)
- University of Applied Sciences Leiden (NL)
- Université Bourgogne Franche-Comté (FR)
- State Key Laboratory of Synthetic Chemistry (CN)
Publication Details
- Journal
- Angewandte Chemie
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1002/ange.202514884
- Primary Topic
- Metal complexes synthesis and properties
- Type
- article
- Field-Weighted Citation Impact
- 0.00