Use of snake antivenom in the Region of the Americas: a systematic review

Antivenom therapy remains central to the management of <i>Bothrops</i> envenomation. However, challenges persist in treatment outcomes and long-term sequelae. Addressing these challenges requires ongoing research to strengthen antivenom manufacturing, explore adjunct therapies and improve post-envenomation care. Substantial heterogeneity study methods and reported outcomes, precluded the ability to conduct pooled analyses and generalize findings.