Integration of gut microbiome and lipid metabolism reveals the anti-cancer effects of pentadecanoic acid on bladder cancer

Collectively, our findings demonstrate that PEA mitigates BC by reshaping the gut microbiome and modulating lipid metabolism, providing new insights into its molecular and therapeutic potential.

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Publication Details

Journal
BMC Medicine
Published
2025-12-03
DOI
https://doi.org/10.1186/s12916-025-04554-5
Citations
1
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.81
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article

Integration of gut microbiome and lipid metabolism reveals the anti-cancer effects of pentadecanoic acid on bladder cancer

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1 citations
BMC Medicine
Gut microbiota and health
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Integration of gut microbiome and lipid metabolism reveals the anti-cancer effects of pentadecanoic acid on bladder cancer

Yingzhou Shen, Anke Wesselius, Richard T. Bryan, Guiju Sun, Kar Keung Cheng, Nicholas David James, Shaokang Wang, Maurice Petrus Zeegers, Lianmin Chen, Jing Sui, Hui Xia, Wenchao Li, Xiangdong Wang, Yang Yu, Ya‐Ting Chen, Qirong Qin, Evan Yi-Wen Yu, Hao Zhang, Shujin Wang
article en
1 citations

Abstract

Collectively, our findings demonstrate that PEA mitigates BC by reshaping the gut microbiome and modulating lipid metabolism, providing new insights into its molecular and therapeutic potential.

BMC MedicineVol. 24(1)
Tufts University (US), Institute of Cancer Research (GB), Anhui Medical University (CN), Nanjing University of Information Science and Technology (CN), Maastricht University (NL), Zhongda Hospital Southeast University (CN), Jean Mayer Human Nutrition Research Center on Aging (US), The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Changzhou No.2 People's Hospital (CN), Anshan Hospital (CN), Southeast University (CN), University of Birmingham (GB), Nanjing Medical University (CN), Chongqing Medical University (CN), Nanjing University (CN)
Openalex Percentile: Top 21%
Gut microbiota and health
0.81
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