Multiple Breath Washout in Primary Ciliary Dyskinesia: Potential for Lung Disease Monitoring
MBW, particularly LCI, shows promise as a noninvasive sensitive marker of early lung disease in PCD. However, its long-term utility in tracking PCD lung disease remain unclear. Further genotype-stratified, longitudinal studies are needed to confirm its clinical value and optimize its application in PCD management.
Authors
- Samantha Irving (ORCID: https://orcid.org/0000-0003-1861-592X)
- Claire Hogg (ORCID: https://orcid.org/0000-0002-8368-5994)
- S.B. Carr (ORCID: https://orcid.org/0000-0003-0580-2478)
- Laura Venditto
- Andrew Bush (ORCID: https://orcid.org/0000-0001-6756-9822)
- Laura Gardner (ORCID: https://orcid.org/0000-0003-4556-5155)
- Michele Arigliani (ORCID: https://orcid.org/0000-0002-5366-4594)
Institutions
- Guy's and St Thomas' NHS Foundation Trust (GB)
- Royal Brompton & Harefield NHS Foundation Trust (GB)
- Great Ormond Street Hospital (GB)
- Great Ormond Street Hospital for Children NHS Foundation Trust (GB)
- Harefield Hospital (GB)
- Lung Institute (US)
- University College London (GB)
Publication Details
- Journal
- Pediatric Pulmonology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/ppul.71422
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 0.00