Treatment effectiveness and preference in patients with schizophrenia switched from oral standard of care atypical antipsychotics to aripiprazole once-monthly: a brief report over a six-month period

Transitioning to AOM from oral antipsychotics in schizophrenia patients was associated with significant improvements in clinical outcomes, symptom severity, and treatment satisfaction, with a favorable safety and tolerability profile. These findings support the use of AOM in early-stage schizophrenia and highlight its potential to enhance long-term adherence and functional recovery. Further long-term studies are warranted to assess the durability of these benefits and their impact on relapse prevention and quality of life.

Authors

Institutions

Publication Details

Journal
Frontiers in Psychiatry
Published
2025-12-03
DOI
https://doi.org/10.3389/fpsyt.2025.1680394
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Treatment effectiveness and preference in patients with schizophrenia switched from oral standard of care atypical antipsychotics to aripiprazole once-monthly: a brief report over a six-month period

Giovanni Martinotti, Mauro Pettorruso, Giulia Giovannetti, Andrea Miuli et al.
Frontiers in Psychiatry
Schizophrenia research and treatment
article

Treatment effectiveness and preference in patients with schizophrenia switched from oral standard of care atypical antipsychotics to aripiprazole once-monthly: a brief report over a six-month period

Giovanni Martinotti, Mauro Pettorruso, Giulia Giovannetti, Andrea Miuli, Gianluca Mancusi, Daniele Di Battista, Teresa Di Crosta, Ornella Di Marco, Marco Alessandrini
article en

Abstract

Transitioning to AOM from oral antipsychotics in schizophrenia patients was associated with significant improvements in clinical outcomes, symptom severity, and treatment satisfaction, with a favorable safety and tolerability profile. These findings support the use of AOM in early-stage schizophrenia and highlight its potential to enhance long-term adherence and functional recovery. Further long-term studies are warranted to assess the durability of these benefits and their impact on relapse prevention and quality of life.

Frontiers in PsychiatryVol. 16
University of Chieti-Pescara (IT), ASL Roma (IT), Azienda Sanitaria Locale Roma 3 (IT)
Otsuka Pharmaceutical, H. Lundbeck A/S
Openalex Percentile: Top 55%
Schizophrenia research and treatment
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Treatment effectiveness and preference in patients with schizophrenia switched from oral standard of care atypical antipsychotics to aripiprazole once-monthly: a brief report over a six-month period — Giovanni Martinotti, Mauro Pettorruso, et al. · Frontiers in Psychiatry (2025) | TGRS Research Map | TGRS