Ruthenium Complexes in Protein Science: Heading a New Generation of Therapeutic and Analytical Tools

Ruthenium complexes are distinguished by their versatile coordination chemistry, redox behaviors and photochemical properties. In recent years, this tunability has enabled precise control over their interactions with peptides and proteins, opening new avenues in therapeutic and analytical applications. This minireview provides a concise overview of the growing role of ruthenium complexes in protein science, with a focus on latest advances in protein targeting, inhibition, labelling, and sensing.

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Publication Details

Journal
Angewandte Chemie International Edition
Published
2025-12-02
DOI
https://doi.org/10.1002/anie.202514884
Citations
2
Primary Topic
Metal complexes synthesis and properties
Type
article
Field-Weighted Citation Impact
2.09
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article

Ruthenium Complexes in Protein Science: Heading a New Generation of Therapeutic and Analytical Tools

Sylvestre Bonnet, Liyan Zhang, Yun Chen
2 citations
Angewandte Chemie International Edition
Metal complexes synthesis and properties
2.09
article

Ruthenium Complexes in Protein Science: Heading a New Generation of Therapeutic and Analytical Tools

Sylvestre Bonnet, Liyan Zhang, Yun Chen
article en
2 citations

Abstract

Ruthenium complexes are distinguished by their versatile coordination chemistry, redox behaviors and photochemical properties. In recent years, this tunability has enabled precise control over their interactions with peptides and proteins, opening new avenues in therapeutic and analytical applications. This minireview provides a concise overview of the growing role of ruthenium complexes in protein science, with a focus on latest advances in protein targeting, inhibition, labelling, and sensing.

Angewandte Chemie International EditionVol. 65(4)
Leiden University (NL), Nanyang Technological University (SG), University of Applied Sciences Leiden (NL), Université Bourgogne Franche-Comté (FR), State Key Laboratory of Synthetic Chemistry (CN)
Openalex Percentile: Top 10%
Metal complexes synthesis and properties
2.09
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