Processed silkworm powder (Hongjam) ameliorates metabolic dysfunction-associated steatotic liver disease via GPR35/PKA and SIRT1/AMPK pathways
These findings suggest that Hongjam and its fibroin-derived peptide exert protective metabolic effects by modulating lipid metabolism, inflammation, and glucose homeostasis. Together, they highlight the potential of Hongjam as a functional food ingredient for the prevention of MASLD.
Authors
- Moon-Young Song (ORCID: https://orcid.org/0000-0001-9311-5146)
- You-Kyung Jang (ORCID: https://orcid.org/0009-0002-4965-8615)
- Eun‐Hee Kim (ORCID: https://orcid.org/0000-0002-8523-0440)
- Seungwon Lee (ORCID: https://orcid.org/0000-0002-0413-0510)
- Da-Young Lee (ORCID: https://orcid.org/0000-0001-7655-6740)
- Hye-Rin Ahn
- Young-Min Han
- Eun-Ji Go
- Seok‐Ho Kim (ORCID: https://orcid.org/0000-0002-2180-8442)
Institutions
- Korea Pharma (South Korea) (KR)
- CHA University (KR)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-12-03
- DOI
- https://doi.org/10.3389/fnut.2025.1727043
- Primary Topic
- Silk-based biomaterials and applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00