Transient elastography and fibrosis-4 index as predictors of hepatocellular carcinoma in hepatitis C virus patients with sustained virological response

In cACLD-HCV SVR patients, pre-treatment or 1-year-EOT LSM ≥ 20 kPa and FIB-4 ≥ 3.25 but not their delta was associated with HCC. A single measure of LSM ≥ 20 kPa or FIB-4 ≥ 3.25, either pre-treatment or 1-year-EOT, would be necessary to predict the incidence of HCC in people with HCV-SVR.

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Publication Details

Journal
World Journal of Gastroenterology
Published
2025-12-03
DOI
https://doi.org/10.3748/wjg.v31.i45.112318
Primary Topic
Hepatitis C virus research
Type
article
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article

Transient elastography and fibrosis-4 index as predictors of hepatocellular carcinoma in hepatitis C virus patients with sustained virological response

Hugo Perazzo, Lúcia Willadino Braga, Cristiane Alves Villela‐Nogueira, Flávia Fernandes et al.
World Journal of Gastroenterology
Hepatitis C virus research
article

Transient elastography and fibrosis-4 index as predictors of hepatocellular carcinoma in hepatitis C virus patients with sustained virological response

Hugo Perazzo, Lúcia Willadino Braga, Cristiane Alves Villela‐Nogueira, Flávia Fernandes, Paula Estefany Batista E Silva, Helena Peixoto, Gustavo Pereira, Juliana Barrocas, José Silva, Livia Villela-Nogueira, Miriam Chinzon
article en

Abstract

In cACLD-HCV SVR patients, pre-treatment or 1-year-EOT LSM ≥ 20 kPa and FIB-4 ≥ 3.25 but not their delta was associated with HCC. A single measure of LSM ≥ 20 kPa or FIB-4 ≥ 3.25, either pre-treatment or 1-year-EOT, would be necessary to predict the incidence of HCC in people with HCV-SVR.

World Journal of GastroenterologyVol. 31(45)
Universidade Federal do Rio de Janeiro (BR), Hospital Universitário Pedro Ernesto (BR), Hospital Geral de Bonsucesso (BR), Instituto Evandro Chagas (BR), Universidade Federal do Estado do Rio de Janeiro (BR)
Openalex Percentile: Top 50%
Hepatitis C virus research
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Transient elastography and fibrosis-4 index as predictors of hepatocellular carcinoma in hepatitis C virus patients with sustained virological response — Hugo Perazzo, Lúcia Willadino Braga, et al. · World Journal of Gastroenterology (2025) | TGRS Research Map | TGRS