The global immune-nutrition-inflammation index predicts pathological response and survival in esophageal squamous cell carcinoma treated with neoadjuvant immunochemotherapy
Pretreatment GINI is a promising biomarker for predicting pathological response and survival outcomes in locally advanced ESCC patients treated with nICT. A high GINI level is significantly associated with treatment resistance and poorer prognosis, suggesting its potential utility in risk stratification and guiding individualized treatment strategies.
Authors
- Zhien Feng (ORCID: https://orcid.org/0000-0003-1952-6734)
- Zhixin Huang (ORCID: https://orcid.org/0000-0001-8568-9000)
- Jiazhou Xiao
- Yifei Tu
- Bo Liu (ORCID: https://orcid.org/0000-0002-2393-117X)
- Huihan Yi (ORCID: https://orcid.org/0000-0002-7403-2801)
Institutions
- Fujian Medical University (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-12-03
- DOI
- https://doi.org/10.3389/fnut.2025.1717477
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fujian Provincial Health Commission