Relationship between impaired cerebral lymphatic function and iron deposition, blood flow in VaD: a clinical MRI study
Our results demonstrated that altered lymphatic function is a key pathological factor in VaD, and reduced cerebral blood flow may play a role in this process. These findings provide a theoretical basis for identifying new targets in the treatment of VaD.
Authors
- Zhongling Zhang (ORCID: https://orcid.org/0000-0002-2539-0389)
- Jun‐Yan Xi (ORCID: https://orcid.org/0000-0001-7473-7783)
- Cong Pang (ORCID: https://orcid.org/0000-0003-1016-655X)
- Shangjie Chen (ORCID: https://orcid.org/0000-0001-8414-7074)
- Long Yuan (ORCID: https://orcid.org/0000-0002-9774-3446)
- Haoran Zhang (ORCID: https://orcid.org/0000-0002-3283-5630)
- Jinping Xu
- Huixing Wu (ORCID: https://orcid.org/0009-0001-2491-2384)
- Yushuang Liu
- Yingqi Lu
Institutions
- Harbin Medical University (CN)
- Chinese Academy of Sciences (CN)
- Shenzhen Bao'an District People's Hospital (CN)
- Shenzhen Institutes of Advanced Technology (CN)
- First Affiliated Hospital of Harbin Medical University (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-12-03
- DOI
- https://doi.org/10.3389/fnins.2025.1666038
- Citations
- 1
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.91
Funders
- National Natural Science Foundation of China
- Guangzhou Municipal Science and Technology Project
- Sanming Project of Medicine in Shenzhen
- Basic and Applied Basic Research Foundation of Guangdong Province