Astragalin attenuates caerulein-induced acute pancreatitis by targeting the NLRP3 signaling pathway and gut microbiota
Collectively, these findings identify astragalin as a promising therapeutic agent for AP, targeting both the NLRP3 signaling cascade and gut microbial homeostasis.
Authors
- Yan Jia (ORCID: https://orcid.org/0000-0001-9338-5859)
- Yilin Huang (ORCID: https://orcid.org/0000-0002-3556-0628)
- Hanyue Wang (ORCID: https://orcid.org/0000-0002-0695-9218)
- Peiyan Chen (ORCID: https://orcid.org/0000-0002-0752-9375)
- Honghui Liu (ORCID: https://orcid.org/0000-0003-2845-1009)
- Ya Liu (ORCID: https://orcid.org/0000-0002-0750-4979)
- Yuxin Shi (ORCID: https://orcid.org/0009-0008-7108-1246)
- Jie Peng (ORCID: https://orcid.org/0000-0003-4040-0327)
- Jie Wang (ORCID: https://orcid.org/0000-0001-5442-9505)
Institutions
- Central South University (CN)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- Bioresources and Bioprocessing
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1186/s40643-025-00977-3
- Citations
- 2
- Primary Topic
- Pancreatitis Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- Key Project of Research and Development Plan of Hunan Province
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Natural Science Foundation of Hunan Province