Why we do need explainable AI for healthcare

The recent uptake in certified Artificial Intelligence (AI) tools for healthcare applications has renewed the debate around their adoption. Explainable AI, the sub-discipline promising to render AI devices more transparent and trustworthy, has also come under scrutiny as part of this discussion. Some experts in the medical AI space debate the reliability of Explainable AI techniques, expressing concerns on their use and inclusion in guidelines and standards. Revisiting such criticisms, this article offers a balanced perspective on the utility of Explainable AI, focusing on the specificity of clinical applications of AI and placing them in the context of healthcare interventions. Against its detractors and despite valid concerns, we argue that the Explainable AI research program is still central to human-machine interaction and ultimately a useful tool against loss of control, a danger that cannot be prevented by rigorous clinical validation alone.

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Publication Details

Journal
Diagnostic and Prognostic Research
Published
2025-12-01
DOI
https://doi.org/10.1186/s41512-025-00209-4
Citations
4
Primary Topic
Explainable Artificial Intelligence (XAI)
Type
article
Field-Weighted Citation Impact
9.92
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article

Why we do need explainable AI for healthcare

Tabea E. Röber, Giovanni Cinà, Rob Goedhart, Ş. İlker Birbil
4 citations
Diagnostic and Prognostic Research
Explainable Artificial Intelligence (XAI)
9.92
article

Why we do need explainable AI for healthcare

Tabea E. Röber, Giovanni Cinà, Rob Goedhart, Ş. İlker Birbil
article en
4 citations

Abstract

The recent uptake in certified Artificial Intelligence (AI) tools for healthcare applications has renewed the debate around their adoption. Explainable AI, the sub-discipline promising to render AI devices more transparent and trustworthy, has also come under scrutiny as part of this discussion. Some experts in the medical AI space debate the reliability of Explainable AI techniques, expressing concerns on their use and inclusion in guidelines and standards. Revisiting such criticisms, this article offers a balanced perspective on the utility of Explainable AI, focusing on the specificity of clinical applications of AI and placing them in the context of healthcare interventions. Against its detractors and despite valid concerns, we argue that the Explainable AI research program is still central to human-machine interaction and ultimately a useful tool against loss of control, a danger that cannot be prevented by rigorous clinical validation alone.

Diagnostic and Prognostic ResearchVol. 9(1)
Amsterdam University Medical Centers (NL), University of Amsterdam (NL)
Openalex Percentile: Top 2%
Explainable Artificial Intelligence (XAI)
9.92
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