Electrochemical Intramolecular Aminobromination of Alkenes
A versatile electrochemical method for the intramolecular aminobromination of alkenes has been developed. The method provides access to five‐, six‐, and seven‐membered heterocycles by exploiting tetrabutylammonium bromide as an electrolyte and bromine source. The mild electrochemical generation of Br 2 plausibly allows the formation of a cyclic bromonium intermediate, as supported by density functional theory calculations.
Authors
- Marta Papis (ORCID: https://orcid.org/0000-0003-3730-9936)
- Giovanni Poli (ORCID: https://orcid.org/0000-0002-7356-1568)
- Sara Colombo (ORCID: https://orcid.org/0009-0002-6128-7394)
- Gianluigi Broggini (ORCID: https://orcid.org/0000-0003-2492-5078)
- Alessandro Contini (ORCID: https://orcid.org/0000-0002-4394-8956)
- Leonardo Lo Presti (ORCID: https://orcid.org/0000-0001-6361-477X)
- Camilla Loro (ORCID: https://orcid.org/0000-0001-9616-2335)
- Giovanni Macetti (ORCID: https://orcid.org/0000-0001-9935-7955)
- Davide Spanu (ORCID: https://orcid.org/0000-0001-7948-2839)
- Emanuele Cartamina (ORCID: https://orcid.org/0009-0006-5233-9155)
Institutions
- University of Insubria (IT)
- University of Lisbon (PT)
- University of Milan (IT)
Publication Details
- Journal
- European Journal of Organic Chemistry
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1002/ejoc.202500808
- Primary Topic
- Radical Photochemical Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Università degli Studi di Milano
- Papua New Guinea University of Technology
- Università degli Studi dell'Insubria