Single-cell RNA sequencing reveals heterogeneity among AT2 epithelial cells in the lung adenocarcinoma microenvironment
This comprehensive single-cell analysis increases our understanding of AT2 cells molecular and dynamics of metastatic lung cancer. In summary, single-cell RNA profiling of LUAD offers valuable prognostic insights based on AT2 cell types and identifies potential biomarkers for therapeutic responses, aiding the future development of LUAD treatment strategies.
Authors
- Zimeng Cao
- Xue‐Feng Bai (ORCID: https://orcid.org/0000-0001-9476-8376)
- Yuncai Xiao (ORCID: https://orcid.org/0000-0003-0171-9693)
- Jiong Cai (ORCID: https://orcid.org/0000-0002-0185-445X)
- Jing Li (ORCID: https://orcid.org/0009-0003-6463-2082)
- Wei Zhou (ORCID: https://orcid.org/0000-0002-4920-8094)
- Gang Cao
Institutions
- Chinese Academy of Sciences (CN)
- Huazhong Agricultural University (CN)
- Shenzhen Institutes of Advanced Technology (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-12-03
- DOI
- https://doi.org/10.3389/fimmu.2025.1735459
- Citations
- 1
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.81