Outcomes of Ventricular Tachycardia Ablation in Cardiac Laminopathy: An Updated Systematic Review and Single‐Arm Meta‐Analysis

In LMNA-related cardiomyopathy, catheter ablation is associated with high VT recurrence, limited long-term success, and substantial cardiovascular mortality and transplantation rates, underscoring the importance of ICD implantation and the need for alternative strategies, including variant-specific and molecularly targeted therapies.

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Publication Details

Journal
Journal of Cardiovascular Electrophysiology
Published
2025-12-02
DOI
https://doi.org/10.1111/jce.70193
Primary Topic
Cardiac Arrhythmias and Treatments
Type
article
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article

Outcomes of Ventricular Tachycardia Ablation in Cardiac Laminopathy: An Updated Systematic Review and Single‐Arm Meta‐Analysis

Konstantinos C. Siontis, Iuri Ferreira Félix, John Giudicessi, Abhishek Deshmukh et al.
Journal of Cardiovascular Electrophysiology
Cardiac Arrhythmias and Treatments
article

Outcomes of Ventricular Tachycardia Ablation in Cardiac Laminopathy: An Updated Systematic Review and Single‐Arm Meta‐Analysis

Konstantinos C. Siontis, Iuri Ferreira Félix, John Giudicessi, Abhishek Deshmukh, Ikram ul Haq, Michael John Ackerman, Ramin Garmany, Matteo Castrichini, Ammar M. Killu, Vanessa Karlinski Vizentin, Trung Huynh, Whitney Rose Swain
article en

Abstract

In LMNA-related cardiomyopathy, catheter ablation is associated with high VT recurrence, limited long-term success, and substantial cardiovascular mortality and transplantation rates, underscoring the importance of ICD implantation and the need for alternative strategies, including variant-specific and molecularly targeted therapies.

Journal of Cardiovascular ElectrophysiologyVol. 37(2)
Heart Rhythm Society (US), Mayo Clinic (US), WinnMed (US), Mayo Clinic in Arizona (US), Mayo Clinic in Florida (US)
Openalex Percentile: Top 45%
Cardiac Arrhythmias and Treatments
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Outcomes of Ventricular Tachycardia Ablation in Cardiac Laminopathy: An Updated Systematic Review and Single‐Arm Meta‐Analysis — Konstantinos C. Siontis, Iuri Ferreira Félix, et al. · Journal of Cardiovascular Electrophysiology (2025) | TGRS Research Map | TGRS