Retrospective analysis of clinical laboratory parameters in Han Wistar rat controls
This analysis provides a comprehensive overview of parameter variability and offers critical guidance for parameters which need to be controlled when utilizing historical control data to establish reference intervals or generate virtual control groups.
Authors
- Annika Kreuchwig (ORCID: https://orcid.org/0000-0001-6513-9693)
- Paolo Piraino (ORCID: https://orcid.org/0009-0009-3933-9726)
- Guillemette Duchâteau-Nguyen (ORCID: https://orcid.org/0009-0002-3602-8104)
- Wolfgang Muster (ORCID: https://orcid.org/0000-0002-9832-6257)
- Markus Schaefer (ORCID: https://orcid.org/0000-0002-0422-7523)
- Rupert Kellner (ORCID: https://orcid.org/0000-0002-6807-8731)
- Dragomir Draganov (ORCID: https://orcid.org/0000-0002-4271-9799)
- Nelly Simetska
- Frank Bringezu (ORCID: https://orcid.org/0000-0002-3628-6317)
- Sylvia E. Escher (ORCID: https://orcid.org/0000-0001-9616-527X)
- Thomas Steger‐Hartmann (ORCID: https://orcid.org/0000-0003-4258-3008)
- Nils Oberhauser
- Alexander Amberg (ORCID: https://orcid.org/0000-0001-9923-0137)
Institutions
- Roche (Switzerland) (CH)
- Novartis (Switzerland) (CH)
- Merck KGaA, Darmstadt (Germany) (DE)
- Center of Technology and Engineering for Nuclear Projects (RO)
- Fraunhofer Institute for Toxicology and Experimental Medicine (DE)
- Sanofi (Germany) (DE)
- Bayer (Germany) (DE)
Publication Details
- Journal
- Frontiers in Toxicology
- Published
- 2025-12-03
- DOI
- https://doi.org/10.3389/ftox.2025.1684191
- Primary Topic
- Veterinary Pharmacology and Anesthesia
- Type
- article
- Field-Weighted Citation Impact
- 0.00