Subtype-specific prognostic implications of plasma-detected PIK3CA mutations in Vietnamese breast cancer patients
Plasma-detected <i>PIK3CA</i> mutations, particularly E545K and H1047R, exhibited subtype-specific associations with clinical outcomes, indicating that plasma analysis may provide complementary information for prognostic assessment in metastatic BC.
Authors
- Lê Hữu Song (ORCID: https://orcid.org/0000-0003-2056-8499)
- Đồng Văn Quyền (ORCID: https://orcid.org/0000-0003-1002-7517)
- Ngo Tat Trung (ORCID: https://orcid.org/0000-0001-9808-1176)
- Đinh Thị Thảo (ORCID: https://orcid.org/0009-0002-4749-2949)
Institutions
- Vietnam Military Medical University (VN)
- Vietnamese - German Center of Excellence in Medical Research (VN)
- 108 Military Central Hospital (VN)
- Vietnam Academy of Science and Technology (VN)
- Hanoi University of Science and Technology (VN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-12-03
- DOI
- https://doi.org/10.3389/fonc.2025.1663823
- Primary Topic
- PI3K/AKT/mTOR signaling in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00