Case Report: A rare case of bilateral primary Müllerian adenosarcoma of the ovary with Uncommon extensive metastasis and GNAQ mutation

We describe a unique case of ovarian adenosarcoma presenting with bilateral ovarian involvement, manifesting at the more advanced stage IIIC, notably in the absence of sarcomatous overgrowth (SO). Moreover, we report for the first time the presence of LVI and the <i>GNAQ</i> missense variant in ovarian adenosarcoma.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-12-03
DOI
https://doi.org/10.3389/fonc.2025.1657939
Primary Topic
Uterine Myomas and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Case Report: A rare case of bilateral primary Müllerian adenosarcoma of the ovary with Uncommon extensive metastasis and GNAQ mutation

Huihua He, Honglin Yan, Shuying Ai, Song Li et al.
Frontiers in Oncology
Uterine Myomas and Treatments
article

Case Report: A rare case of bilateral primary Müllerian adenosarcoma of the ovary with Uncommon extensive metastasis and GNAQ mutation

Huihua He, Honglin Yan, Shuying Ai, Song Li, Xiuyun Zhang, Jingping Yuan
article en

Abstract

We describe a unique case of ovarian adenosarcoma presenting with bilateral ovarian involvement, manifesting at the more advanced stage IIIC, notably in the absence of sarcomatous overgrowth (SO). Moreover, we report for the first time the presence of LVI and the <i>GNAQ</i> missense variant in ovarian adenosarcoma.

Frontiers in OncologyVol. 15
Wuhan University (CN), Renmin Hospital of Wuhan University (CN)
Health Commission of Hubei Province
Openalex Percentile: Top 52%
Uterine Myomas and Treatments
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