Exercise-responsive circTSN as a potential systemic biomarker during COPD rehabilitation
circTSN may serve as a molecular sensor linking changes in the pulmonary environment to the body's broader adaptive responses during exercise therapy. This discovery offers crucial mechanistic insight into how exercise benefits individuals with COPD, highlighting circTSN as a valuable target for future molecular monitoring and therapeutic strategies.
Authors
- Lei Zhao (ORCID: https://orcid.org/0000-0001-9737-2721)
- Fan Bai (ORCID: https://orcid.org/0000-0002-7036-9140)
- Haizhu Zeng (ORCID: https://orcid.org/0000-0001-7391-221X)
- Huali Zhang (ORCID: https://orcid.org/0000-0002-0788-7092)
- Xiaoxiang Liu
- Rreshma Akter
Institutions
- Second Military Medical University (CN)
- The First People's Hospital of Changde (CN)
- Shanghai Pudong New Area Gongli Hospital (CN)
- Morgan State University (US)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-12-03
- DOI
- https://doi.org/10.3389/fmed.2025.1735444
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shanghai Pudong New Area Health Commission