Alpinetin Targets Mitophagy Pathways to Mitigate Parkinson's Disease Progression
Our findings demonstrate that Alpinetin has significant therapeutic potential for PD, likely mediated through the regulation of mitophagy and dopaminergic synapses. This study elucidates the molecular targets and mechanisms of Alpinetin, providing a solid foundation for its further investigation as an anti-PD agent.
Authors
- Haijun Hu
- Xuesong Shan (ORCID: https://orcid.org/0000-0002-1339-7452)
- Shenglan Zhang (ORCID: https://orcid.org/0000-0001-7129-3443)
- Dan Huang (ORCID: https://orcid.org/0000-0003-4221-574X)
- Lieliang Zhang (ORCID: https://orcid.org/0009-0005-5700-6096)
- Hong Zhu (ORCID: https://orcid.org/0000-0001-7289-083X)
- Zhen Shen (ORCID: https://orcid.org/0000-0001-7572-9195)
- Yayu Chen (ORCID: https://orcid.org/0009-0002-0220-7219)
- Yonglin Liang
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Second Affiliated Hospital of Nanchang University (CN)
- Education Department of Jiangxi Province (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1002/cns.70676
- Citations
- 1
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 1.35