Modulating the gut-bladder axis: fecal transplantation protects antibiotic-treated mice from E. coli cystitis via the Ahr/Prg4 pathway
These findings provide a theoretical foundation for the clinical diagnosis and treatment of bacterial cystitis by leveraging the gut microbiota and their metabolites as promising therapeutic targets. Video Abstract.
Authors
- Yi Yan Yang (ORCID: https://orcid.org/0000-0002-1871-5448)
- Mimi L.K. Tang (ORCID: https://orcid.org/0000-0002-3839-5293)
- Haoran Chen (ORCID: https://orcid.org/0000-0001-7566-3368)
- Yasheng Li (ORCID: https://orcid.org/0009-0002-5703-6445)
- Jianjuan Lu
- Ning Yang (ORCID: https://orcid.org/0000-0002-9907-4688)
- Q Zhang
- Ting Wu (ORCID: https://orcid.org/0000-0002-5350-1277)
- Yuxian Shen (ORCID: https://orcid.org/0000-0002-0916-0743)
- Liang Yu (ORCID: https://orcid.org/0000-0002-8351-3332)
- Hui Zhang (ORCID: https://orcid.org/0000-0002-5626-3542)
- Yanyan Liu (ORCID: https://orcid.org/0000-0002-1405-7345)
- Bao Meng
- Jiabin Li (ORCID: https://orcid.org/0000-0002-6539-1802)
- Yahong Zheng
- Long Gao (ORCID: https://orcid.org/0009-0006-0246-3123)
- Xufeng Li (ORCID: https://orcid.org/0000-0002-1822-2416)
- L Liu
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Microbiome
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1186/s40168-025-02267-8
- Citations
- 1
- Primary Topic
- Urinary Tract Infections Management
- Type
- article
- Field-Weighted Citation Impact
- 1.35