NCF2 as a Novel Diagnostic Biomarker in Ulcerative Colitis: Linking Macrophage Infiltration to Immune Dysregulation via Multi-Omics Analysis
CD274, MMP1, NCF2, PLAU can serve as hub genes associated with UC. Among these, NCF2 stands out as a particularly promising target for further research into the underlying mechanisms of UC. Additionally, NCF2 may play a role in the development and progression of UC by modulating macrophage infiltration.
Authors
- Jianwei Zhu (ORCID: https://orcid.org/0000-0001-6782-2023)
- Bingcheng Wang (ORCID: https://orcid.org/0000-0002-3258-9812)
- Haiyan Liu (ORCID: https://orcid.org/0000-0002-4652-469X)
- Jianan Ye (ORCID: https://orcid.org/0000-0002-6672-8040)
- Fang Zhang (ORCID: https://orcid.org/0000-0001-5622-0422)
- Yuanyuan Li (ORCID: https://orcid.org/0009-0001-4265-4008)
Institutions
- Shanghai Tenth People's Hospital (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Command Hospital Air Force (IN)
- Yangzhou University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-12-01
- DOI
- https://doi.org/10.2147/jir.s552678
- Citations
- 1
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.80