Dosimetric evaluation of megavoltage X‐ray and proton minibeam radiation therapy in brain tumor‐bearing canines

In this dosimetric comparison of MBRT and pMBRT for the treatment of spontaneous canine brain tumors, the distinct in-depth physical behavior of X-ray and proton minibeams makes each modality more suitable for specific target locations to achieve optimal dose distributions. These findings provide valuable guidance for future veterinary clinical trials and represent an important step toward the clinical implementation of MBRT and pMBRT.

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Publication Details

Journal
Medical Physics
Published
2025-12-01
DOI
https://doi.org/10.1002/mp.70186
Primary Topic
Radiation Therapy and Dosimetry
Type
article
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article

Dosimetric evaluation of megavoltage X‐ray and proton minibeam radiation therapy in brain tumor‐bearing canines

Yolanda Prezado, Jérôme Benoît, Alfredo Fernandez‐Rodriguez, Sébastien Perrot
Medical Physics
Radiation Therapy and Dosimetry
article

Dosimetric evaluation of megavoltage X‐ray and proton minibeam radiation therapy in brain tumor‐bearing canines

Yolanda Prezado, Jérôme Benoît, Alfredo Fernandez‐Rodriguez, Sébastien Perrot
article en

Abstract

In this dosimetric comparison of MBRT and pMBRT for the treatment of spontaneous canine brain tumors, the distinct in-depth physical behavior of X-ray and proton minibeams makes each modality more suitable for specific target locations to achieve optimal dose distributions. These findings provide valuable guidance for future veterinary clinical trials and represent an important step toward the clinical implementation of MBRT and pMBRT.

Medical PhysicsVol. 52(12)
Centre National de la Recherche Scientifique (FR), Inserm (FR), Université Paris-Saclay (FR), Xunta de Galicia (ES), Laboratoire de Génétique & Evolution des Populations Végétales (FR), Center for Research in Molecular Medicine and Chronic Diseases (ES), Informatique Electromagnetisme Electronique Analyse Numerique (France) (FR), Instituto de Investigación Sanitaria de Santiago (ES), Institut Curie (FR)
Openalex Percentile: Top 44%
Radiation Therapy and Dosimetry
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Dosimetric evaluation of megavoltage X‐ray and proton minibeam radiation therapy in brain tumor‐bearing canines — Yolanda Prezado, Jérôme Benoît, et al. · Medical Physics (2025) | TGRS Research Map | TGRS