Two trajectories of lumbar disc degeneration from adolescence to adulthood: a 23-year longitudinal MRI study
Progression of DD is an inevitable but individually variable process. Early-onset DD appears to lead to a more widespread pattern, whereas later-onset DD progresses more rapidly but remains confined to the lower lumbar spine. No direct relationship between structural progression and LBP could be determined.
Authors
- Hannu Kautiainen (ORCID: https://orcid.org/0000-0003-0786-0858)
- Dietrich Schlenzka (ORCID: https://orcid.org/0000-0001-6205-0351)
- Anni Aavikko (ORCID: https://orcid.org/0000-0002-8501-6735)
- Teija Lund (ORCID: https://orcid.org/0000-0001-9519-9355)
- Martina Lohman
- Leena Ristolainen (ORCID: https://orcid.org/0000-0002-3041-260X)
Institutions
- University of Helsinki (FI)
- Helsinki University Hospital (FI)
- Kuopio University Hospital (FI)
- Invalidisäätiö (FI)
- Päijät-Hämeen Keskussairaala (FI)
- Folkhälsans Forskningscentrum (FI)
- Hospital District of Helsinki and Uusimaa (FI)
Publication Details
- Journal
- European Spine Journal
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1007/s00586-025-09641-y
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00