Cinchonidine enhances intracellular erythromycin activity against Rhodococcus equi
Our findings highlight CIN as a redox-active adjuvant that potentiates erythromycin's intracellular efficacy against R. equi. This combinatorial approach targets redox homeostasis and enhances bacterial clearance, providing a promising strategy against multidrug-resistant intracellular pathogens.
Authors
- Álvaro Mourenza (ORCID: https://orcid.org/0000-0003-4926-3891)
- Jesús F. Aparicio (ORCID: https://orcid.org/0000-0003-4242-4701)
- Blanca Lorente-Torres (ORCID: https://orcid.org/0000-0003-0131-7520)
- Michal Letek (ORCID: https://orcid.org/0000-0002-9509-5174)
- Luís M. Mateos (ORCID: https://orcid.org/0000-0001-7763-582X)
- Jesús Llano-Verdeja (ORCID: https://orcid.org/0009-0007-3238-5565)
- Pablo Castañera (ORCID: https://orcid.org/0009-0008-4314-4457)
- Helena Á. Ferrero (ORCID: https://orcid.org/0009-0003-1582-2779)
- Sergio Fernández-Martínez (ORCID: https://orcid.org/0009-0001-9642-9850)
- Farzaneh Javadimarand (ORCID: https://orcid.org/0000-0001-9619-6631)
Institutions
- Universidad de León (MX)
- Universidad de León (ES)
Publication Details
- Journal
- Journal of Microbiology Immunology and Infection
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1016/j.jmii.2025.12.003
- Citations
- 1
- Primary Topic
- Infectious Disease Case Reports and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.40