Robot-assisted total hip arthroplasty following gene therapy for hemophilia a arthropathy: a case report
This pioneering case demonstrates the potential safety and efficacy of combining gene therapy with minimally invasive RA-THA for HA hip arthropathy. The integrated approach significantly reduced dependence on exogenous FVIII and enabled precise anatomical reconstruction.
Authors
- Jing Dai
- Yanyan Shao (ORCID: https://orcid.org/0000-0002-2708-8474)
- Zhijie Chen
- Xuefeng Wang (ORCID: https://orcid.org/0000-0001-5775-408X)
- Chuan He (ORCID: https://orcid.org/0000-0002-8532-2898)
- Chuanlong Wu (ORCID: https://orcid.org/0000-0002-7513-8536)
Institutions
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
Publication Details
- Journal
- Arthroplasty
- Published
- 2025-12-03
- DOI
- https://doi.org/10.1186/s42836-025-00348-5
- Primary Topic
- Hemophilia Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China
- National Health Commission of the People's Republic of China