Prognostic implications of quantified coronary atherosclerosis and myocardial perfusion in diabetes
Coronary atherosclerotic plaque burden appears as an important predictor of long-term cardiovascular outcomes both in diabetic and non-diabetic patients. In patients with diabetes, normal myocardial perfusion does not necessarily imply low event risk, partly attributable to higher coronary plaque burden. Quantitative imaging methods for detailed CAD phenotyping shed light on the complex relationship between diabetes and clinical outcomes.
Authors
- Teemu Maaniitty (ORCID: https://orcid.org/0000-0001-5819-4635)
- Antti Saraste (ORCID: https://orcid.org/0000-0003-2488-0893)
- Paul Knaapen (ORCID: https://orcid.org/0000-0001-8038-7898)
- Ruurt Jukema (ORCID: https://orcid.org/0000-0002-3212-2665)
- Ibrahim Danad (ORCID: https://orcid.org/0000-0002-3140-1320)
- Ralf W. Sprengers (ORCID: https://orcid.org/0000-0003-1463-1842)
- Matias Mäenpää (ORCID: https://orcid.org/0000-0001-6147-2421)
- Juhani Knuuti (ORCID: https://orcid.org/0000-0003-3156-9593)
- Roel S. Driessen (ORCID: https://orcid.org/0000-0003-3971-0109)
- Pieter G. Raijmakers (ORCID: https://orcid.org/0000-0002-5225-3240)
- Pepijn A. van Diemen (ORCID: https://orcid.org/0000-0001-5482-6201)
- Sarah Bär (ORCID: https://orcid.org/0000-0003-0045-6596)
- Jeroen J. Bax
Institutions
- Radboud University Nijmegen (NL)
- University of Turku (FI)
- Leiden University Medical Center (NL)
- University Hospital of Bern (CH)
- Turku University Hospital (FI)
- Radboud University Medical Center (NL)
- Turku PET Centre (FI)
- Amsterdam University Medical Centers (NL)
- Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1186/s12933-025-03006-x
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Foundation for Cardiovascular Research
- Turun Yliopisto
- Sydäntutkimussäätiö