Topographic analysis of vascular changes in retrograde trans-synaptic degeneration
RTSD demonstrated relatively modest vascular compromise compared to NAION, which is presumed to reflect secondary changes due to reduced metabolic demand following retrograde neuronal degeneration. Quantitative structure-vascular analysis using RTSD as a reference model may aid in distinguishing secondary degeneration from primary ischemic injury in optic neuropathies.
Authors
- Yeji Moon (ORCID: https://orcid.org/0000-0002-9553-2231)
Institutions
- Ulsan College (KR)
- Asan Medical Center (KR)
- University of Ulsan (KR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1371/journal.pone.0337283
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00