Traumatic Cervical Spinal Cord Injuries

Traumatic cervical spinal cord injury (cSCI) is a devastating condition associated with significant morbidity and long-term disability. Surgical decompression remains the cornerstone of management; however, the potential role of duraplasty as an adjunctive procedure remains controversial. Proponents argue that duraplasty alleviates intraspinal pressure, enhances spinal cord perfusion, and reduces secondary ischemic injury by expanding the dural space and mitigating post-traumatic edema. Emerging clinical and preclinical data suggest that duraplasty may improve neurological outcomes by optimizing cerebrospinal fluid dynamics and reducing ischemia-induced neuronal apoptosis. However, critics highlight significant risks, including cerebrospinal fluid leakage, pseudomeningocele formation, infection, and intracranial hypotension, which may outweigh its theoretical benefits. This comparative article critically examines the pathophysiological rationale, existing evidence, and ongoing controversies in favour or against widespread adoption of duroplasty in cervical spinal cord trauma.

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Publication Details

Journal
Clinical Spine Surgery A Spine Publication
Published
2025-11-11
DOI
https://doi.org/10.1097/bsd.0000000000001980
Primary Topic
Spinal Cord Injury Research
Type
article
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article

Traumatic Cervical Spinal Cord Injuries

Jake McDonnell, Stacey L. Darwish, Joseph Simon Butler, Jordan Pim
Clinical Spine Surgery A Spine Publication
Spinal Cord Injury Research
article

Traumatic Cervical Spinal Cord Injuries

Jake McDonnell, Stacey L. Darwish, Joseph Simon Butler, Jordan Pim
article en

Abstract

Traumatic cervical spinal cord injury (cSCI) is a devastating condition associated with significant morbidity and long-term disability. Surgical decompression remains the cornerstone of management; however, the potential role of duraplasty as an adjunctive procedure remains controversial. Proponents argue that duraplasty alleviates intraspinal pressure, enhances spinal cord perfusion, and reduces secondary ischemic injury by expanding the dural space and mitigating post-traumatic edema. Emerging clinical and preclinical data suggest that duraplasty may improve neurological outcomes by optimizing cerebrospinal fluid dynamics and reducing ischemia-induced neuronal apoptosis. However, critics highlight significant risks, including cerebrospinal fluid leakage, pseudomeningocele formation, infection, and intracranial hypotension, which may outweigh its theoretical benefits. This comparative article critically examines the pathophysiological rationale, existing evidence, and ongoing controversies in favour or against widespread adoption of duroplasty in cervical spinal cord trauma.

Clinical Spine Surgery A Spine PublicationVol. 39(2)
University College Dublin (IE), Mater Misericordiae University Hospital (IE)
Openalex Percentile: Top 48%
Spinal Cord Injury Research
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Traumatic Cervical Spinal Cord Injuries — Jake McDonnell, Stacey L. Darwish, et al. · Clinical Spine Surgery A Spine Publication (2025) | TGRS Research Map | TGRS