A population-based analysis of a risk stratification system for predicting radiotherapy benefits in invasive breast carcinoma of no special type with medullary pattern

We developed and validated a prognostic nomogram for IBC-NST with medullary pattern that accurately stratifies patients by risk. Our findings indicate that radiotherapy is associated with a survival benefit primarily in low-risk patients, offering a practical tool to optimize RT personalization and avoid overtreatment in high-risk individuals.

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Publication Details

Journal
European journal of medical research
Published
2025-12-02
DOI
https://doi.org/10.1186/s40001-025-03558-4
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
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article

A population-based analysis of a risk stratification system for predicting radiotherapy benefits in invasive breast carcinoma of no special type with medullary pattern

Lizhao Wang, Heyan Chen, Yan Yu, Jian Zhang et al.
European journal of medical research
Breast Cancer Treatment Studies
article

A population-based analysis of a risk stratification system for predicting radiotherapy benefits in invasive breast carcinoma of no special type with medullary pattern

Lizhao Wang, Heyan Chen, Yan Yu, Jian Zhang, Ke Wang, Guanqun Ge, Jianjun He
article en

Abstract

We developed and validated a prognostic nomogram for IBC-NST with medullary pattern that accurately stratifies patients by risk. Our findings indicate that radiotherapy is associated with a survival benefit primarily in low-risk patients, offering a practical tool to optimize RT personalization and avoid overtreatment in high-risk individuals.

European journal of medical researchVol. 31(1)
First Affiliated Hospital of Xi'an Jiaotong University (CN)
Openalex Percentile: Top 53%
Breast Cancer Treatment Studies
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