Dolutegravir-based therapy, diet, physical activity and weight gain: a 48-week prospective cohort in South Africa

Weight gain in people transitioning to TLD was not strongly linked to lifestyle. Interventions targeting diet and exercise may be unlikely to mitigate weight gain in this population.

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Publication Details

Journal
JAIDS Journal of Acquired Immune Deficiency Syndromes
Published
2025-12-02
DOI
https://doi.org/10.1097/qai.0000000000003812
Primary Topic
HIV-related health complications and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Dolutegravir-based therapy, diet, physical activity and weight gain: a 48-week prospective cohort in South Africa

Mark Jacob Siedner, Deenan Pillay, Bethany Hedt‐Gauthier, François Venter et al.
JAIDS Journal of Acquired Immune Deficiency Syndromes
HIV-related health complications and treatments
article

Dolutegravir-based therapy, diet, physical activity and weight gain: a 48-week prospective cohort in South Africa

Mark Jacob Siedner, Deenan Pillay, Bethany Hedt‐Gauthier, François Venter, Mahomed‐Yunus S. Moosa, Ravindra K. Gupta, Suzanne M. McCluskey, Jennifer Manne‐Goehler, Nomathemba Chandiwana, Vincent C. Marconi, Geoffrey Chen, Gugulethu Shazi, Smart Z. Mabweazara, Dessie Tien
article en

Abstract

Weight gain in people transitioning to TLD was not strongly linked to lifestyle. Interventions targeting diet and exercise may be unlikely to mitigate weight gain in this population.

JAIDS Journal of Acquired Immune Deficiency Syndromes
Brigham and Women's Hospital (US), Harvard University (US), Desmond Tutu HIV Foundation (ZA), Mbarara University of Science and Technology (UG), Emory University (US), University of the Witwatersrand (ZA), University of Cambridge (GB), Massachusetts General Hospital (US), Africa Health Research Institute (ZA), University College London (GB), University of KwaZulu-Natal (ZA)
Openalex Percentile: Top 46%
HIV-related health complications and treatments
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