Sustained superior humoral immune responses of mRNA vaccines compared to Sputnik V viral vector COVID-19 vaccines in naïve and convalescent populations
mRNA vaccination provides markedly superior and sustained antibody responses compared to adenoviral vector vaccine, which is particularly relevant for long-term protection strategies.
Authors
- Zain Khalil (ORCID: https://orcid.org/0009-0007-4692-1998)
- Charles Gleason
- Brian Lerman
- Diego Ojeda (ORCID: https://orcid.org/0000-0001-6528-6087)
- Komal Srivastava
- Ana S. Gonzalez‐Reiche (ORCID: https://orcid.org/0000-0003-3583-4497)
- Anass Abbad (ORCID: https://orcid.org/0000-0002-4617-0473)
- Florian Krammer (ORCID: https://orcid.org/0000-0003-4121-776X)
- Ana Fernández-Sesma (ORCID: https://orcid.org/0000-0002-3405-6702)
- Andrea V. Gamarnik (ORCID: https://orcid.org/0000-0002-9789-4105)
- Gagandeep Singh (ORCID: https://orcid.org/0000-0003-3260-2631)
- Viviana Simon (ORCID: https://orcid.org/0000-0002-6416-5096)
- Jordan Ehrenhaus
Institutions
- Consejo Nacional de Investigaciones Científicas y Técnicas (AR)
- Fundación Instituto Leloir (AR)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Vaccine
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1016/j.vaccine.2025.128018
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00