IGF-II-secreting bladder tumour presenting as a fall in a 91-year-old
Unexplained and recurrent episodes of hypoglycaemia should raise clinical suspicion of a paraneoplastic process that requires further investigation. It is important to maintain a broad range of differentials when approaching a frail patient with recurrent hypoglycaemia. Management should be guided by discussion with a multidisciplinary team and patient preference. IGF-II-secreting tumours are widely associated with mesenchymal tumours; however, this case presents a rare possible association with bladder tumours. Surgical resection of NICTH tumours is the mainstay of treatment, but when it is not feasible, other medical management should be explored.
Authors
- Shwetha Sairam
- Imaan Hirji (ORCID: https://orcid.org/0009-0004-5965-8808)
- Hiro Khoshnaw
Institutions
- Royal Surrey NHS Foundation Trust (GB)
Publication Details
- Journal
- Endocrinology Diabetes and Metabolism Case Reports
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1530/edm-25-0090
- Primary Topic
- Growth Hormone and Insulin-like Growth Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00