Medetomidine-vatinoxan-methadone and acepromazine-methadone: comparison of sedative and cardiovascular properties as a preanaesthetic medication in healthy dogs

When used as a preanaesthetic medication in combination with methadone, medetomidine-vatinoxan causes faster onset of sedation, without statistically significant differences in cardiovascular interventions, compared to acepromazine.

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Publication Details

Journal
Acta veterinaria Scandinavica
Published
2025-12-02
DOI
https://doi.org/10.1186/s13028-025-00844-3
Primary Topic
Veterinary Pharmacology and Anesthesia
Type
article
Field-Weighted Citation Impact
0.00
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article

Medetomidine-vatinoxan-methadone and acepromazine-methadone: comparison of sedative and cardiovascular properties as a preanaesthetic medication in healthy dogs

Kati Salla, Vuokko Pekkola, Marja Riitta Raekallio, Jaan Lepajõe et al.
Acta veterinaria Scandinavica
Veterinary Pharmacology and Anesthesia
article

Medetomidine-vatinoxan-methadone and acepromazine-methadone: comparison of sedative and cardiovascular properties as a preanaesthetic medication in healthy dogs

Kati Salla, Vuokko Pekkola, Marja Riitta Raekallio, Jaan Lepajõe, Ira J. Kallio-Kujala
article en

Abstract

When used as a preanaesthetic medication in combination with methadone, medetomidine-vatinoxan causes faster onset of sedation, without statistically significant differences in cardiovascular interventions, compared to acepromazine.

Acta veterinaria ScandinavicaVol. 68(1)
University of Helsinki (FI)
Openalex Percentile: Top 57%
Veterinary Pharmacology and Anesthesia
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