Alterations in dynamic regional homogeneity and functional connectivity in lung cancer patients with bone metastasis pain
This study demonstrates abnormal dynamic brain activity within visual, affective, and sensorimotor networks in patients with BMP. These findings suggest that dReHo/dFC variability may serve as a neuroimaging biomarker for BMP diagnosis and disease monitoring. Furthermore, they provide new insights into the neurophysiological mechanisms of BMP and identify promising targets for neuromodulation-based therapeutic interventions.
Authors
- Jing Yang (ORCID: https://orcid.org/0000-0003-0620-4306)
- Jiuquan Zhang (ORCID: https://orcid.org/0000-0003-0239-6988)
- Jing Zhang (ORCID: https://orcid.org/0000-0002-6076-7321)
- Tan Cheng
- Lin Tang (ORCID: https://orcid.org/0000-0001-6511-1607)
- Xiaoyu Zhou (ORCID: https://orcid.org/0000-0001-9911-3088)
- Hong Yu
- Yong Tan (ORCID: https://orcid.org/0000-0003-1219-4773)
- Daihong Liu (ORCID: https://orcid.org/0000-0001-5606-4394)
- Yu Tang (ORCID: https://orcid.org/0000-0002-5020-332X)
Institutions
- Chongqing University (CN)
- Chongqing Cancer Hospital (CN)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1016/j.brainresbull.2025.111670
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00