Quyushengxin formula restores the integrity of intestinal barrier by regulating the gut microbiota to ameliorate DSS-induced ulcerative colitis in mice
The mechanism underlying the efficacy of QYSXF involves restoring the composition of the gut microbiota to improve intestinal barrier, reducing the release of proinflammatory cytokines, and ultimately alleviating UC. This research not only confirms the therapeutic potential of QYSXF in UC treatment but also, more importantly, highlights the critical role of gut microbiota regulation in restoring barrier dysfunction and mitigating inflammatory responses involved in the pathogenesis of UC.
Authors
- Changpeng Han
- Qian Shi (ORCID: https://orcid.org/0000-0003-2634-9553)
- Dan Gan (ORCID: https://orcid.org/0000-0002-6715-0666)
- Haojie Yang (ORCID: https://orcid.org/0000-0002-8633-2713)
- Zhenyi Wang (ORCID: https://orcid.org/0000-0002-4146-9433)
- Yiheng Yang (ORCID: https://orcid.org/0009-0001-1618-8250)
- Biao Liang
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Yueyang Hospital (CN)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1016/j.jep.2025.120992
- Citations
- 1
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.81