Quyushengxin formula restores the integrity of intestinal barrier by regulating the gut microbiota to ameliorate DSS-induced ulcerative colitis in mice

The mechanism underlying the efficacy of QYSXF involves restoring the composition of the gut microbiota to improve intestinal barrier, reducing the release of proinflammatory cytokines, and ultimately alleviating UC. This research not only confirms the therapeutic potential of QYSXF in UC treatment but also, more importantly, highlights the critical role of gut microbiota regulation in restoring barrier dysfunction and mitigating inflammatory responses involved in the pathogenesis of UC.

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Publication Details

Journal
Journal of Ethnopharmacology
Published
2025-12-02
DOI
https://doi.org/10.1016/j.jep.2025.120992
Citations
1
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.81
Controls
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article

Quyushengxin formula restores the integrity of intestinal barrier by regulating the gut microbiota to ameliorate DSS-induced ulcerative colitis in mice

Changpeng Han, Qian Shi, Dan Gan, Haojie Yang et al.
1 citations
Journal of Ethnopharmacology
Gut microbiota and health
0.81
article

Quyushengxin formula restores the integrity of intestinal barrier by regulating the gut microbiota to ameliorate DSS-induced ulcerative colitis in mice

Changpeng Han, Qian Shi, Dan Gan, Haojie Yang, Zhenyi Wang, Yiheng Yang, Biao Liang
article en
1 citations

Abstract

The mechanism underlying the efficacy of QYSXF involves restoring the composition of the gut microbiota to improve intestinal barrier, reducing the release of proinflammatory cytokines, and ultimately alleviating UC. This research not only confirms the therapeutic potential of QYSXF in UC treatment but also, more importantly, highlights the critical role of gut microbiota regulation in restoring barrier dysfunction and mitigating inflammatory responses involved in the pathogenesis of UC.

Journal of EthnopharmacologyVol. 358
Shanghai University of Traditional Chinese Medicine (CN), Yueyang Hospital (CN)
Openalex Percentile: Top 21%
Gut microbiota and health
0.81
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